A single transparent fee for a complete, synthesis-ready design report. Check amenability before you pay anything — most people should.
No recurring charges. No lock-in. Refund policy published.
Design an ASO →Gene-silencing, splice-switching subtypes, upregulation and experimental modalities.
Reference sequence pulled and annotated automatically.
Sequences generated and optimized for your specific target.
Tm, GC content and self-complementarity for every candidate.
BLAST against the human transcriptome for off-target homology.
Top candidates ranked, each with written design rationale and vendor notation.
Consult Pequliar about your gene or variant for an amenability read.
If it looks amenable, choose “Design ASO”.
Complete PayPal payment and receive a receipt.
Your ranked design report arrives within minutes.
Historically this first step was buried inside programmes costing $700K–$1.5M per patient. At $399, a family can at least find out whether the road is worth starting.